FXR受体激动剂 申请号:CN201710639245.2 专利类型:发明申请 公开(公告)日:2017-07-31
状态:寻求转化 转让价格:面议
本发明属于医药技术领域,具体涉及式(I)所示的化合物、其药学上可接受的盐、酯或其立体异构体,R1、R2、R3、M1、M2、m、n、Q、L、环A、环B、环C如说明书中所定义;本发明还涉及这些化合物的制备方法及在用于制备治疗和/或预防由FXR受体介导的非酒精性脂肪肝、原发性胆汁性肝硬化、脂质代谢紊乱、糖尿病并发症及恶性肿瘤等相关疾病的药物中的应用。
FXR受体激动剂 申请号:CN201710909293.9 专利类型:发明申请 公开(公告)日:
状态:寻求转化 转让价格:面议
本发明属于医药技术领域,具体涉及式(I)所示的化合物、其药学上可接受的盐、酯或其立体异构体,R1、R2、R3、M1、M2、Q、L、环A、环B、m如说明书及权利要求书中所定义;本发明还涉及这些化合物的制备方法、药物制剂及在用于制备治疗和/或预防由FXR受体介导的非酒精性脂肪肝、原发性胆汁性肝硬化、脂质代谢紊乱、糖尿病并发症及恶性肿瘤等相关疾病的药物中的应用。
FXR RECEPTOR AGONIST 申请号:WOCN18094813 专利类型:发明申请 公开(公告)日:2018-07-06
状态:寻求转化 转让价格:面议
The present invention relates to the technical field of pharmacy, and specifically relates to a compound as represented by formula (I), and a pharmaceutically acceptable salt, an ester or stereoiso...
FXIA inhibitor [...]... 申请号:JP2017512780 专利类型:发明授权 公开(公告)日:
状态:寻求转化 转让价格:面议
The present invention provides compounds of Formula (I) or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds a...
FUTURE PRICE PREDICT... 申请号:JP2011268418 专利类型:发明申请 公开(公告)日:
状态:寻求转化 转让价格:面议
PROBLEM TO BE SOLVED : To provide the future price prediction device for a real estate and the financing agreement management device of financing with a real estate as liable assets which can be used...
FUSION PROTEINS 申请号:WOGB18053771 专利类型:发明申请 公开(公告)日:
状态:寻求转化 转让价格:面议
Provided are fusion target-binding proteins comprising a target binding moiety, an intracellular signalling region and a domain that promotes synthesis of arginine or an arginine precursor. The domai...
FUSION PROTEIN POLYN... 申请号:IN201917003657 专利类型:发明申请 公开(公告)日:
状态:寻求转化 转让价格:面议
The invention relates to molecular biology biotechnology medicine veterinary science. A group of inventions is proposed : a fusion protein comprising a ligand to MATN1 protein and a growth factor of ...
FUSION PROTEIN OF IL... 申请号:WOCN18106034 专利类型:发明申请 公开(公告)日:2018-09-17
状态:寻求转化 转让价格:面议
Provided is an immune effector cell expressing a fusion protein. The fusion protein contains a cytokine binding extracellular domain and a signal transduction intracellular domain, wherein the extrac...
FUSED RING COMPOUND ... 申请号:PT11817649 专利类型:发明授权 公开(公告)日:
状态:寻求转化 转让价格:面议
The present invention belongs to the technical field of medicine, relating in particular to : a fused ring compound as represented by Formula (I) for use as a mineralocorticoid receptor antagonist, ...
FUSED RING COMPOUND ... 申请号:EP11817649 专利类型:发明授权 公开(公告)日:2011-08-18
状态:寻求转化 转让价格:面议
The present invention belongs to the technical field of medicine, relating in particular to : a fused ring compound as represented by Formula (I) for use as a mineralocorticoid receptor antagonist, ...