IL13Rα2 PEPTIDE AND ... 申请号:WOEP18080193 专利类型:发明申请 公开(公告)日:
状态:寻求转化 转让价格:面议
The invention relates to a peptide comprising the amino acid sequence SEQ ID NO : 1 or a variant thereof capable of inhibiting IL13/IL13Rα2 signalling. The invention also relates to a fusion protein,...
IL13RALPHA2 PEPTIDE ... 申请号:EP17382737 专利类型:发明申请 公开(公告)日:
状态:寻求转化 转让价格:面议
The invention relates to a peptide comprising the amino acid sequence SEQ ID NO : 1 or a variant thereof capable of inhibiting IL13/IL13Rα2 signalling. The invention also relates to a fusion protein,...
IL-a 15 heterodimer ... 申请号:JP2016544083 专利类型:发明授权 公开(公告)日:2014-12-25
状态:寻求转化 转让价格:面议
The present invention relates to an IL-15 heterodimeric protein and uses thereof and further relates to an IL-15/IL-15R?heterodimeric protein. The IL-15 heterodimeric protein comprises protein (I) and...
IL-6R ANTIBODY AND A... 申请号:CA3075561 专利类型:发明申请 公开(公告)日:
状态:寻求转化 转让价格:面议
Provided in the present invention are an IL-6R antibody and antigen binding fragment thereof. The IL-6R antibody is an alpaca-derived antibody, chimeric antibody and humanized antibody. Also provided...
IL-6R ANTIBODY AND A... 申请号:CA3075561 专利类型:发明申请 公开(公告)日:2018-09-12
状态:寻求转化 转让价格:面议
Provided in the present invention are an IL-6R antibody and antigen binding fragment thereof. The IL-6R antibody is an alpaca-derived antibody, chimeric antibody and humanized antibody. Also provided...
IL-6R ANTIBODY AND A... 申请号:WOCN18105180 专利类型:发明申请 公开(公告)日:2018-09-12
状态:寻求转化 转让价格:面议
Provided in the present invention are an IL-6R antibody and antigen binding fragment thereof. The IL-6R antibody is an alpaca-derived antibody, chimeric antibody and humanized antibody. Also provided...
IL-6 ANTAGONISTS AND... 申请号:EP18197185 专利类型:发明申请 公开(公告)日:
状态:寻求转化 转让价格:面议
IL-6 antagonists are provided that are specific for binding to site II of IL-6. Methods of using such inhibitors to treat IL-6 related diseases, e.g. disease of the eye such as diabetic macular edema...
IL-5 ANTIBODY, ANTI... 申请号:WOCN18108240 专利类型:发明申请 公开(公告)日:
状态:寻求转化 转让价格:面议
Provided are an IL-5 antibody, an antigen binding fragment thereof, and a medical application therefor. The present invention comprises a mouse-derived antibody containing an IL-5 antibody CDR regio...
IL-4R的融合蛋白及其应用 申请号:CN201811083679.X 专利类型:发明申请 公开(公告)日:
状态:寻求转化 转让价格:面议
本发明提供表达一种融合蛋白的免疫效应细胞,所述融合蛋白包含细胞因子结合胞外结构域和信号转导胞内结构域,其中所述胞外结构域为IL4受体胞外结构域,所述胞内结构域为IL‑21受体胞内结构域。所述免疫效应细胞在实体瘤的肿瘤微环境中具备显著的抗肿瘤能力,从而不仅在体外对实体瘤细胞有效,在体内对实体瘤细胞也具备优异的杀伤效果。本发明还提供包含所述免疫效应细胞的药物组合物以及它们的应用。
IL-36γ作为动脉粥样硬化的标志物 申请号:CN201810848296.0 专利类型:发明申请 公开(公告)日:
状态:寻求转化 转让价格:面议
本发明提出了一种动脉粥样硬化生物标志物。根据本发明的实施例,所述动脉粥样硬化生物标志物具有下列序列的至少之一:(1)SEQ ID NO : 1所示的氨基酸序列;(2)与(1)具有至少70%同一性的氨基酸序列,优选地,具有至少80%同一性的氨基酸序列,优选地,具有至少85%同一性的氨基酸序列,优选地,具有至少90%同一性的氨基酸序列,优选地,具有至少95%同一性的氨基酸序列,更优选地,具有至少99%...