T cell receptor α ge... 申请号：JP2016516173 专利类型：发明授权 公开（公告）日：2014-05-28
状态：寻求转化 转让价格：面议
Disclosed herein are compositions for inactivating the human TCR-alpha gene comprising engineered LAGLIDADG homing endonucleases (LHEs) and their derivatives, particularly derived from members of the...
T cell receptor spec... 申请号：JP2018532590 专利类型：发明申请 公开（公告）日：2016-12-22
状态：寻求转化 转让价格：面议
The present invention relates to T cell receptors (TCRs) which bind the HLA-A*02 restricted peptide SLLMWITQC derived from the cancer antigen NY-ESO-1. Said TCRs may comprise mutations within the alph...
T cell receptor (TCR... 申请号：KR1020187031670 专利类型：发明申请 公开（公告）日：2016-03-31
状态：寻求转化 转让价格：面议
The present invention relates to T cells, in particular a non-activated T cell, comprising an exogenous nucleic acid encoding a T cell Receptor (TCR) specific for a virus. An embodiment of the inven...
T cell receptor 申请号：JP2018549900 专利类型：发明申请 公开（公告）日：
状态：寻求转化 转让价格：面议
The present invention relates to T cell receptors (TCRs) which bind the HLA-A*02 restricted peptide SLYNTVATL (SEQ ID NO : 1) derived from the HIV Gag gene product, p17. Said TCRs comprise non-natur...
T cell receptor 申请号：JP2018552859 专利类型：发明申请 公开（公告）日：
状态：寻求转化 转让价格：面议
The present invention relates to T cell receptors (TCRs) that bind the HLA-A*02 restricted peptide GVYDGREHTV (SEQ ID NO : 1) derived from the germline cancer antigen MAGE A4. Said TCRs may comprise ...
T cell activation in... 申请号：JP2017043440 专利类型：发明授权 公开（公告）日：
状态：寻求转化 转让价格：面议
The present invention provides a bispecific biologic comprising a ligand specific for CTLA-4 and a ligand specific for a pMHC complex.
T cell activation an... 申请号：JP2017506345 专利类型：发明授权 公开（公告）日：2015-08-03
状态：寻求转化 转让价格：面议
The present invention generally relates to novel bispecific antigen binding molecules for T cell activation and re-direction to specific target cells. In addition, the present invention relates to po...
T CELL RECEPTORS REC... 申请号：JP2018187094 专利类型：发明申请 公开（公告）日：2018-10-02
状态：寻求转化 转让价格：面议
PROBLEM TO BE SOLVED : To provide immunological compositions and improved methods for treating cancer for patients that lack HLA-A2 expression. SOLUTION : The invention provides an isolated or p...
T CELL RECEPTORS 申请号：EP14748262 专利类型：发明授权 公开（公告）日：
状态：寻求转化 转让价格：面议
The present invention relates to T cell receptors (TCRs) which bind the HLA-A2 restricted FMNKFIYEI (158-166) peptide epitope derived from α Fetoprotein (AFP). Certain preferred TCRs of the invention ...
T CELL RECEPTORS 申请号：IN201817041886 专利类型：发明申请 公开（公告）日：2018-11-05
状态：寻求转化 转让价格：面议
The present invention relates to T cell receptors (TCRs) which bind the HLA-A0201 restricted peptide GVYDGEEHSV (SEQ ID NO : 1) derived from the MAGE-B2 protein. The TCRs of the invention demonstrate...
