The present invention relates to a method for effectively measuring a six-cancer risk degree according to individuals by a portable terminal user using a multi-stage analysis algorithm based on an elastic net technique, and supplying a counseling support tool with a doctor with regard to health management and whether an additional complete medical checkup is required, and relates to a method for supplying a cancer-screening sub-service and system thereof, by which an individual concentration is calculated in a smart phone by correcting a difference by applying individual characteristics (for example, a disease-related individual characteristic such as gender, age, smoking state, and the like), using a measurement value in the concentration inside a serum of protein biomarkers properly selected according to the individual user through an analysis algorithm system set in a predetermined location of a portable terminal such that the portable terminal user can directly measure the risk degree of six cancers such as a lung cancer, liver cancer, colorectal cancer, prostate cancer, stomach cancer, and the like, of the portable terminal user at the same time, wherein the data is used as an original value, and sensitivity whether there is a cancer, specificity, a false positive rate, a false negative rate, a positive predictive value, an ROC curve, and the like are calculated, so cancer risk can be measured with a score from zero to one. Accordingly, a health management system-possible check system and a future-oriented medical treatment system are established by a vitro diagnosis system, a remote treatment and a u-health which are convenient and easy in quality using a portable terminal having a six-cancer personalized diagnosis support system capable of applying regular cancer screening and health management.(13) Biomarker information DB(16) Algorism information DB(17) Report information DB(AA) Calculating(BB) Storing result candidate Data(CC) Storing(DD, EE, GG) Input(FF) Calculating measurment unit(HH) Repeat(II) Risk degree determining unit(JJ) Output(KK) Result outputCOPYRIGHT KIPO 2015