专利名称 | METHOD OF PREDICTING CARDIOVASCULAR COMPLICATIONS IN PATIENTS WITH ISCHEMIC HEART DISEASE | ||
申请号 | RU2017146915 | 申请日 | |
公开(公告)号 | RU2670689C9 | 公开(公告)日 | 2017-12-28 |
申请(专利权)人 | 发明人 | Shlyakhto Evgenij Vladimirovich; Sergeeva Elena Gennadevna; Berkovich Olga Aleksandrovna; Ionova Zhanna Igorevna; Baranova Elena Ivanovna | |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
FIELD : medicine.SUBSTANCE : invention relates to medicine, namely cardiology, cardiac surgery, angiology and rehabilitation. Determine the presence of type 2 diabetes, heredity, burdened with IHD, LDL cholesterol, factor of smoking and, additionally, the presence of polymorphisms of the receptor activator gene of peroxisome proliferation PPAR-γ2 and PPAR-α and the number of affected coronary arteries at the time of manifestation of the disease. Then, calculate the discriminant function according to the original formula and, with its positive values, predict CC in patients with IHD, with its negative values, the absence of CC.EFFECT : method makes it possible to predict the CC in patients with IHD with different coronary artery disease severity with high accuracy, which allows selecting a priority group of patients for personalized secondary prevention of adverse CC.1 cl, 2 dwg, 1 tbl, 2 ex |
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