FIELD : medicine.SUBSTANCE : presented group of inventions refers to the field of molecular biology and medicine. Method and a set of primers and probes for identifying immunogen DNA discrepancies in donor – recipient pairs are proposed. Conduct DNA testing for the presence of polymorphism alleles in the genes ERBB2, HMNA1, MYO1G, KIAA1551, TOR3A, CLYBL, C19ORF48, TRIM22, PRCP, SSR1, WNK1, TRIM42, KIAA0020, HIVEP1, NISCH, UGT2B17, CCL4, NCAPD3, NDC80, WDR27 and the establishment of immunogenic combinations of the state of the studied genes in the donor and recipient, where immunogenic is considered a condition in which the recipient carries at least one immunogenic allele of MAG, and the donor is homozygous for the non-immunogenic allele, in the case of the UGT2B17 gene, a condition is considered to be immunogenic in which the gene is detected in recipient and is not detected in the donor.EFFECT : proposed group of inventions provides a quick, easy and cost-effective method for the genotyping of minor histocompatibility antigens (MHA), which allows genotyping polymorphisms with high specificity and sensitivity in one step.6 cl, 3 dwg, 6 ex, 4 tbl