专利名称 | SALT OF BENZOPIPERIDINE DERIVATIVE AND CRYSTAL FORM THEREOF, AND METHOD FOR PREPARING SALT AND CRYSTAL FORM THEREOF | ||
申请号 | WOCN18091781 | 申请日 | |
公开(公告)号 | WO2018233591A1 | 公开(公告)日 | 2018-06-19 |
申请(专利权)人 | 发明人 | YOU Lingfeng; SHAO Cheng; FENG Jun | |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
Disclosed are a salt of a benzopiperidine derivative and a crystal form thereof, and a method for preparing the salt and the crystal form thereof. Specifically, disclosed are an L-lysinate of (E)-3-(4-((1R, 3R)-2-(4-cyclopropyl phenyl)-6-(1-ethyl-1H-pyrazole-4-yl)-3-methyl-1, 2, 3, 4-tetrahydroisoquinoline-1-yl)phenyl)acrylic acid, a I crystal form thereof, and a preparation method therefor. The compound represented by formula (I) and the I crystal form thereof have good stabilization, has a simple process easy to operate, and can be better used in clinical treatment. |
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