| 专利名称 | 5-aryl-1H-pyrrole-3-carbonitrile and a pharmaceutical product using the same | ||
| 申请号 | US14994360 | 申请日 | |
| 公开(公告)号 | US10173977B2 | 公开(公告)日 | 2016-01-13 |
| 申请(专利权)人 | 发明人 | Tomomi Ikemoto; Hideya Mizufune; Toshiaki Nagata; Misayo Sera; Naohiro Fukuda; Takeshi Yamasaki | |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
The present invention provides a production method of a sulfonylpyrrole compound useful as a pharmaceutical product, a production method of an intermediate used for the method, and a novel intermediate. The present invention relates to a method of producing sulfonylpyrrole compound (VIII), which includes reducing compound (III) and hydrolyzing the reduced product to give compound (IV), subjecting compound (IV) to a sulfonylation reaction to give compound (VI), and subjecting compound (VI) to an amination reaction. |
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