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专利概况
专利名称 5-aryl-1H-pyrrole-3-carbonitrile and a pharmaceutical product using the same
申请号 US14994360 申请日
公开(公告)号 US10173977B2 公开(公告)日 2016-01-13
申请(专利权)人 发明人 Tomomi Ikemoto; Hideya Mizufune; Toshiaki Nagata; Misayo Sera; Naohiro Fukuda; Takeshi Yamasaki
专利来源 国家知识产权局 转化方式
摘要

The present invention provides a production method of a sulfonylpyrrole compound useful as a pharmaceutical product, a production method of an intermediate used for the method, and a novel intermediate. The present invention relates to a method of producing sulfonylpyrrole compound (VIII), which includes reducing compound (III) and hydrolyzing the reduced product to give compound (IV), subjecting compound (IV) to a sulfonylation reaction to give compound (VI), and subjecting compound (VI) to an amination reaction.

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