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专利概况
专利名称 SYNTHETIC LETHALITY AND TREATMENT OF CANCER
申请号 RU2015118294 申请日
公开(公告)号 RU2676697C2 公开(公告)日 2013-10-30
申请(专利权)人 发明人 BERTOM Lyuk G; PERINPANAYAGAM Konganig Maneka Ann; YAP Chuiee; BOSHAMP Ervan
专利来源 国家知识产权局 转化方式
摘要

FIELD : medicine.SUBSTANCE : present group of inventions relates to medicine, namely to oncology, and concerns the treatment of cancer. For this purpose, cancer patients who are deficient in the isomer of the enzyme N-myristoyltransferase 2 (NMT2) are identified. Treatment of this group of patients is carried out by administering an NMT inhibitor or NMT1 isoenzyme.EFFECT : this provides an increase in the effectiveness of treatment of this group of patients, since cancer deficient in NMT2 is most sensitive to treatment with NMT inhibitors.16 cl, 8 tbl, 38 ex, 42 dwg

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