专利名称 | SYNTHETIC LETHALITY AND TREATMENT OF CANCER | ||
申请号 | RU2015118294 | 申请日 | |
公开(公告)号 | RU2676697C2 | 公开(公告)日 | 2013-10-30 |
申请(专利权)人 | 发明人 | BERTOM Lyuk G; PERINPANAYAGAM Konganig Maneka Ann; YAP Chuiee; BOSHAMP Ervan | |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
FIELD : medicine.SUBSTANCE : present group of inventions relates to medicine, namely to oncology, and concerns the treatment of cancer. For this purpose, cancer patients who are deficient in the isomer of the enzyme N-myristoyltransferase 2 (NMT2) are identified. Treatment of this group of patients is carried out by administering an NMT inhibitor or NMT1 isoenzyme.EFFECT : this provides an increase in the effectiveness of treatment of this group of patients, since cancer deficient in NMT2 is most sensitive to treatment with NMT inhibitors.16 cl, 8 tbl, 38 ex, 42 dwg |
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