专利名称 | A quinazoline derivative of the crystal and its preparation | ||
申请号 | JP2018533210 | 申请日 | |
公开(公告)号 | JP2019500370A | 公开(公告)日 | 2016-12-23 |
申请(专利权)人 | 发明人 | シュー チューティエン; ワン チンユアン; ワン チェンホア | |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
The invention relates to Crystal form I and Crystal form II of dihydrochloride of N-(4-((3-chloro-4-fluorophenyl)amino)-7-((7-methyl-7-azaspiro[3.5]nonan-2-yl)methoxy)quinazoli n-6-yl)acrylamide represented by the following Formula (I), and preparation methods therefor, wherein the Crystal form I has an X-ray powder diffraction pattern having characteristic peaks at the 2 ? positions of 6.0?.2? 7.3?.2? 11.7?.2? 12.9?.2? 18.4?.2? 24.7?.2? and 26.3?.2? as determined by using Cu-K?radiation, and the Crystal form II has an X-ray powder diffraction pattern having characteristic peaks at the 2 ? positions of 5.0?.2? 7.0?.2? 10.1?.2? 17.0?.2? 26.0?.2? and 26.5?.2? as determined by using Cu-K?radiation. |
主管部门:海南中小企业服务 | 建设单位:海南商业联合会
版权所有:海南商业联合会 | 备案号:粤ICP备13083911号(ICP加挂服务)@2017