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专利概况
专利名称 In combination with MRI contrast agent formulations comprising
申请号 JP2018527102 申请日
公开(公告)号 JP2019500333A 公开(公告)日 2016-11-30
申请(专利权)人 发明人 メイジャー アンドレアス・リチャード; ダウェール パリトシュ・ジャヤント; サニング ミッケル・ジェイコブ; グリンゲリ コンチェッタ・バレリア; デシーナ サルバトーレ; キャシディー ディアドラ; ジョーンズ ポール・アレクサンダー
专利来源 国家知识产权局 转化方式
摘要

The present invention relates to in vivo imaging and in particular to magnetic resonance imaging (MRI). Provided by the present invention is a pharmaceutical formulation suitable for use in an MRI procedure and which offers advantages over known such formulations. A particular dose of the pharmaceutical formulation of the invention is also envisioned as well as the use of said dose in a method of in vivo imaging. This present invention provides for simultaneous administration of a liver specific agent and a second MR contrast agent that is capable of better/further enhancing the dynamic vascular phase in a patient. The method of the invention has the advantage of simplicity and patient comfort, compared to sequential injections. Furthermore, the method of the invention provides the advantage that it can enable a lower cumulative dose of contrast agents.

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