专利名称 | P2X4 RECEPTOR ANTAGONIST | ||
申请号 | CA2809113 | 申请日 | |
公开(公告)号 | CA2809113C | 公开(公告)日 | 2011-07-27 |
申请(专利权)人 | 发明人 | USHIODA MASATOSHI; SAKUMA SHOGO; TENDO ATSUSHI; IMAI TOSHIYASU; INOUE KAZUHIDE | |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
A compound having the following formula (II) or a pharmacologically acceptable salt thereof is used as a P2X4 receptor antagonist : wherein each of R11 and R12 is hydrogen, C1-8 alkyl or the like; R13 is hydrogen, C1-8 alkyl or the like; R14 is hydrogen, C1-8 alkyl, C1-8 alkoxy, C1-8 alkyl having 1-3 halogens, C1-8 hydroxyalkyl, halogen, hydroxyl, nitro, cyano, amino, C1-8 alkylamino, benzenesulfonylamino optionally having a substituent, a heterocyclic group op- tionally having a substituent or the like; and the condensed ring consisting of W1 and the neighbor- ing benzene ring is naphthalene, tetrahydronaphthalene, or indan ring. |
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