FIELD : medicine.SUBSTANCE : invention relates to medicine and is intended for the prevention of acute diarrhea in patients with acute myeloblastic leukemia against the background of agranulocytosis. Patients with acute myeloblastic leukemia receiving chemotherapy, on the first day of agranulocytosis, for the prevention of the development of acute diarrhea, 1 tablet of bismuth tripotassium dicitrate 304.6 mg 4 times a day and Saccharomyces Boulardii 500?mg 2 times a day are prescribed to increase the level of neutrophilic leukocytes in peripheral blood to more than 0.5?09/l.EFFECT : method allows to reduce the likelihood of developing diarrhea in patients receiving chemotherapy for acute myeloid leukemia in the state of agranulocytosis.1 cl, 1 ex