专利名称 | METHOD OF SUPPRESSION OF INFLAMMATORY RESPONSE IN PERIODONTAL TISSUES IN AN EXPERIMENT | ||
申请号 | RU2017141975 | 申请日 | |
公开(公告)号 | RU2677642C1 | 公开(公告)日 | 2017-12-01 |
申请(专利权)人 | 发明人 | Malyshev Igor Yurevich; Kalish Sergej Valerevich; Lyamina Svetlana Vladimirovna; Shimanskij Shalva Livanovich; Suvorova Irina Andreevna; Kuznetsova Larisa Vyacheslavovna; Yanushevich Oleg Olegovich | |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
FIELD : medicine.SUBSTANCE : invention relates to medicine, in particular to immunology, and can be used to suppress the inflammatory response in periodontal tissues in an experiment. For this purpose, macrophages polarized in vitro in M2 regulatory phenotype are introduced into the gum, wherein the suspension comprising 250 thousand macrophages in 100?mcl of medium.EFFECT : method allows significantly reducing the leukocyte migration coefficient (LMC) to the gingival surface in experimental LPS-induced inflammation against the background of the introduction of macrophages of M2 regulatory phenotype into the gums in mice.1 cl, 1 tbl, 1 ex |
主管部门:海南中小企业服务 | 建设单位:海南商业联合会
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