专利名称 | Tricyclic compounds and uses thereof in medicine | ||
申请号 | US15541018 | 申请日 | |
公开(公告)号 | US10183917B2 | 公开(公告)日 | 2016-02-05 |
申请(专利权)人 | 发明人 | Xiaojun Wang; Xinye Yang; Shengqiang Pan; Rui Guo; Junwen Wu; Yingjun Zhang; Changchung Cheng | |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
The present invention relates to novel tricyclic compounds which can bind to FXR and act as modulators of the FXR, or a stereoisomer, a geometric isomer, a tautomer, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, and the uses of the compounds for the treatment of diseases and/or conditions mediated by FXR. The invention further provides a pharmaceutical composition containing the compound disclosed herein and a method of treatment of diseases and/or conditions mediated by FXR comprising administering the compound or the pharmaceutical composition. |
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