| 专利名称 | Antibodies against PCSK9 stabilized preparation | ||
| 申请号 | JP2017248606 | 申请日 | |
| 公开(公告)号 | JP6456470B2 | 公开(公告)日 | 2017-12-26 |
| 申请(专利权)人 | 发明人 | スコット・ウォルシュ; ダニエル・ディクス | |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
The present invention provides pharmaceutical formulations comprising a human antibody that specifically binds to human proprotein convertase subtilisin/kexin type 9 (PCSK9). The formulations may contain, in addition to an anti-PCSK9 antibody, at least one amino acid, at least one sugar, or at least one non-ionic surfactant. The pharmaceutical formulations of the present invention exhibit a substantial degree of antibody stability after storage for several months. |
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