您好,欢迎来到海南中小企业大数据中心及公共服务平台!     请登录   免费注册
专利概况
专利名称 METHOD FOR PRODUCING A STABLE PHARMACEUTICAL COMPOSITION PRESENTED AS AN AQUEOUS SOLUTION
申请号 ARP170102733 申请日
公开(公告)号 AR109775A1 公开(公告)日 2017-09-29
申请(专利权)人 发明人
专利来源 国家知识产权局 转化方式
摘要

The invention relates to the chemical and pharmaceutical industry. A method for producing a stabilized pharmaceutical composition in the form of an aqueous solution comprising active ingredients which include succinic acid, inosine, nicotinamide and riboflavin mononucleotide sodium salt, wherein a stabilizing agent is further introduced into the composition as one or more pharmaceutically acceptable ingredients selected from the group consisting of sodium hydroxide, tris-(oxymethyl)aminomethane (TRIS), ethanolamine, diethanolamine, sodium carbonate and meglumine to obtain a stable aqueous solution having a pH value in the range of 6.0 to 8.0; the method further comprises a sterilizing filtration of the resulting dissolved composition, and an additional thermal sterilization at temperatures from 100癈 and an exposure time of 8 minutes to 116癈 and an exposure time of 2 minutes.

参与列表

主管部门:海南中小企业服务 | 建设单位:海南商业联合会

版权所有:海南商业联合会 | 备案号:粤ICP备13083911号(ICP加挂服务)@2017