| 专利名称 | DRUG FILM OF PROLONGED ACTION AND METHOD FOR ITS PREPARATION | ||
| 申请号 | RU2018127796 | 申请日 | |
| 公开(公告)号 | RU2678200C1 | 公开(公告)日 | 2018-07-27 |
| 申请(专利权)人 | 发明人 | Kurganskij Ilya Sergeevich; Fatkulin Renat Rashidovich; Lepekhova Svetlana Aleksandrovna; Makhutov Valerij Nikolaevich; Zaritskaya Larisa Vasilevna; Kostyro Yana Antonovna; Goldberg Oleg Aronovich; Inozemtsev Evgenij Olegovich; Grigorev Evgenij Georgievich | |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
FIELD : medicine.SUBSTANCE : group of inventions relates to medicine. Described is a drug film of prolonged action, which contains the main component in the form of a 30?% aqueous solution of gelatin, auxiliary and drug components. As auxiliary components it contains a 20?% solution of human albumin, saline, powdered polyvinylpyrrolidone, collagen, fibrinogen, thrombin. As a drug component it contains a biologically active substance – vascular endothelial growth factor (VEGF) in the following ratio, wt. parts : 30?% aqueous solution of gelatin – 1.5, 20?% solution of human albumin – 1.0, polyvinylpyrrolidone – 0.1, collagen – 3.0, fibrinogen – 0.125, thrombin – 1.0, vascular endothelial growth factor (VEGF) – 0.02, saline – 10.0. Described is a method for producing a drug film, which provides the possibility of an effective concentration of the active substance in the blood for 7 days.EFFECT : film does not prevent the fusion of the wound edges with each other, contributes to the epithelization of the wound edges on the 7th day of the study.2 cl, 4 dwg, 1 tbl, 2 ex |
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