There is disclosed a coating system practicable for medico-technological products, which method comprises one at least cellulose substance or derivative thereof alone or in combination with other substances. Said coating system favors the release of a drastic substance that it comprises, aiming at the therapy of a disease. The present invention finds application to implantable and non-implantable medico-technological products such as balloons, stents, grafts, supplements and implants of any type.