专利名称 | METHOD FOR PREDICTING RISK OF DEVELOPMENT OF HYPERTENSIVE DISEASE FACTORED IN GENETIC AND ENVIRONMENTAL FACTORS | ||
申请号 | RU2018123944 | 申请日 | |
公开(公告)号 | RU2678441C1 | 公开(公告)日 | 2018-07-02 |
申请(专利权)人 | 发明人 | Churnosov Mikhail Ivanovich; Moskalenko Mariya Ivanovna; Milanova Snezhana Nikolovna; Ponomarenko Irina Vasilevna; Polonikov Aleksej Valerevich | |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
FIELD : medicine.SUBSTANCE : invention relates to the field of medicine, namely to predicting the risk of developing hypertension in individuals of Russian nationality who are residents of the Central Black Earth Oblast. For this purpose carry out the isolation of DNA from peripheral venous blood. Analysis of gene polymorphisms, characterized in analyzing the gene polymorphisms of growth factors rs6214 IGF-1 and rs2981582 FGFR2. Respondent is determined to have environmental risk factors for the development of hypertension in the respondent, namely, to determine the smoking status. Predict the high risk of developing hypertension in identifying a combination of the GG rs6214 IGF-1 genotype, the TT rs2981582 FGFR2 genotype, and a positive smoking status.EFFECT : invention provides criteria for assessing the risk of developing hypertension in this category of patients, taking into account a combination of genetic and environmental factors.1 cl, 3 dwg, 3 ex |
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