FIELD : medicine. SUBSTANCE : invention relates to medicine, in particular, to a pro-liposomal pharmaceutical depot formulation, a method for preparing same, a pro-liposomal non-aqueous base formulation, a method for preparing same, and a kit for administering a hydrophobic active pharmaceutical ingredient. According to the present invention, disclosed are pro-liposomal non-aqueous pharmaceutical depot formulations, containing natural non-synthetic lecithin-based phospholipid, oil as a non-aqueous pharmaceutically acceptable carrier, ethanol as viscosity regulator. EFFECT : implementation of the invention allows to obtain a pro-liposomal non-aqueous depot formulation, ensuring the maintenance of therapeutically effective levels of API for several days, wherein the pro-liposomal depot formulation is a stable, transparent oily solution, characterised by low viscosity. 53 cl, 4 dwg, 17 tbl, 17 ex