Provided are intestinal composite bacteria for the prevention and treatment of digestive tract and/or skin response and use thereof. The composite bacteria include at least one of plant lactobacillus, bifidobacterium longum, lactobacillus johnsonii, bifidobacterium infantis, lactobacillus salivarius, lactobacillus rhamnosus, lactobacillus acidophilus, lactobacillus helveticus, lactobacillus lactis, bifidobacterium lactis, bifidobacterium adolescentis, lactobacillus reuteri, bifidobacterium bifidum, lactobacillus gasseri, lactobacillus casei, lactobacillus paracasei, lactobacillus fermentum, bifidobacterium breve, lactobacillus brevis, bifidobacterium animalis, clostridium butyricum, bacillus licheniformis, lactobacillus delbrueckii and lactobacillus bulgaricus. The composite bacteria are used for controlling and treating digestive tract and skin adverse response.