The present invention describes an approach to the design of temperature regulation systems combining, in a single structure, a heat absorption or release system by fusion or solidification of a particular material and also a particulate oxide that contributes to reflecting infrared radiation. The production of the thermofunctional nanostructure comprises six successive processing steps : a) pre-emulsifying the organic material and dispersing the colloidal oxide nanoparticles in an aqueous phase, the pre-emulsion; b) reducing droplet size in the pre-emulsion by high-pressure homogenisation; c) adsorbing the monomer in the resultant emulsion; d) polymerising and forming thermoftmctional nanostructures; e) cooling the nanosuspension containing the thermofunctional structures; and optionally f) drying the product. The resultant thermofunctional nanostructure can be in the form of a colloidal dispersion in an aqueous medium or of a nanoparticle powder, if the aqueous nanostructure dispersion is subjected to a drying process. This thermofunctional nanostructure can be applied to obtain products in the fields of cosmetics, pharmaceuticals, medical equipment, prostheses, textiles, paints, coatings, composites, packaging, civil engineering, electrical or electronic equipment, the automobile and paper industries.