专利名称 | Tetracyclic bromodomain inhibitors | ||
申请号 | JP2018190645 | 申请日 | |
公开(公告)号 | JP2019014748A | 公开(公告)日 | 2018-10-09 |
申请(专利权)人 | 发明人 | STEVEN D FIDANZE; LIU DACHUN; ROBERT A MANTEI; MCDANIEL KEITH F; JOHN PRATT; GEORGE S SHEPPARD; LE WANG; ANDREW BOGDAN; JOHN H HOLMS; JUSTIN D DIETRICH; JASMINA MARJANOVIC; HASVOLD LISA A; DAI YUJIA | |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
PROBLEM TO BE SOLVED : To provide compounds useful as agents in treatment of diseases, including inflammatory diseases, cancer, and AIDS. SOLUTION : The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, and pharmaceutical compositions comprising the compounds. [Y1 is N or CH; R1 is C1-C3 alkyl or the like; R2 and R6 are each independently H or the like; Y3 is N or substituted/unsubstituted C; Y2 is C(O) or the like; and A1 to A4 are N or substituted/unsubstituted C, provided that zero, one or two of A1 to A4 are N.] SELECTED DRAWING : None COPYRIGHT : (C)2019, JPO&INPIT |
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