FIELD : medicine. SUBSTANCE : invention relates to medicine and is intended to reduce the severity of eosinophilic esophagitis. Therapeutic composition comprising an interieukin-4 receptor (IL-4R) inhibitor, such as an anti-IL-4R antibody or an antigen-binding fragment that specifically binds to IL-4P, is administrated to a subject. EFFECT : method widens the range of therapeutic agents. 17 cl, 4 dwg, 3 ex