A nano-lipid microparticle composition, the nano-lipid microparticle composition consisting of cytarabine, an anthracycline antibiotic, and a nano-lipid microparticle, wherein the cytarabine and the anthracycline antibiotic are co-encapsulated in the nano-lipid microparticle, and the nano-lipid microparticle comprises a charged lipid stabilizer, the effective average particle size thereof being less than 400 nm.