专利名称 | ACTIVE ENANTIOMER OF DODECYL 2-(N, N-DIMETHYLAMINO)-PROPIONATE | ||
申请号 | RU2013119439 | 申请日 | |
公开(公告)号 | RU2679308C2 | 公开(公告)日 | 2011-11-30 |
申请(专利权)人 | 发明人 | DAMAZH Bassam B; MARTIN Richard | |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
FIELD : medicine; pharmaceuticals.SUBSTANCE : group of inventions relates to the field of medicine and chemical-pharmaceutical industry, specifically to a method for increasing the supply of lansoprazole to the bloodstream of a mammal when administered orally, comprising orally administering said mammal a solution of lansoprazole in the presence of 2R-dodecyl-2-(N, N-dimethylamino)-propionate or a salt thereof, having an enantiomeric purity of at least 70?%, to a pharmaceutical solution for oral administration, containing lansoprazole in a mixture with 2R-dodecyl-2-(N, N-dimethylamino)-propionate or a salt thereof, and a mixture of lansoprazole and 2R-dodecyl-2-(N, N-dimethylamino)-propionate or a salt thereof.EFFECT : group of inventions provides an increase in the intake of lansoprazole in the bloodstream of a mammal when administered orally.12 cl, 1 dwg, 1 tbl, 2 ex |
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