FIELD : medicine.SUBSTANCE : invention relates to the field of medicine, namely to diagnosis and gynecology, and is intended to identify the risk of developing a combination of genital endometriosis and endometrial hyperplastic processes in women of Russian nationality, natives of the Central Black Soil Region. To predict the risk of developing a combination of genital endometriosis and endometrial hyperplastic processes, DNA is isolated from peripheral venous blood, then combinations of gene polymorphisms are analyzed rs3756261, rs7753051, rs1544410, rs2090409. When a combination of the G rs3756261 allele with the T rs7753051 allele, with the A rs1544410 allele, and the T rs2090409 allele is detected, the risk of developing a combination of genital endometriosis and endometrial hyperplastic processes in women of Russian nationality born in the Central Black Earth Region is predicted.EFFECT : use of the invention provides a prediction of the risk of developing a combination of genital endometriosis and endometrial hyperplastic processes in women at the preclinical stage.1 cl, 3 ex