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专利概况
专利名称 ENZYME AND METHOD OF PRODUCING OMEGA-3 FATTY ACIDS
申请号 JP2018167853 申请日
公开(公告)号 JP2019022493A 公开(公告)日 2018-09-07
申请(专利权)人 发明人 JAMES ROBERTSON PETRIE; ANNE MAREE MACKENZIE; LIU QING; PUSHKAR SHRESTHA; PETER DAVID NICHOLS; SUSAN IRENE ELLIS BLACKBURN; MAGED PETER MANSOUR; STANLEY SURESH ROBERT; DION MATTHEW FREDERICK FRAMPTON; ZHOU XUE RONG; SURINDER PAL SINGH; CRAIG CHRISTOPHER WOOD
专利来源 国家知识产权局 转化方式
摘要

PROBLEM TO BE SOLVED : To provide an enzyme and method of producing omega-3 fatty acid. SOLUTION : The method is for obtaining cells that can synthesize DPA and comprises : a) a step of introducing an exogenous polynucleotide that encodes a fatty acid elongase having Δ5 elongase activity that can be coupled so as to be activatable by a promoter that can induce the expression the polynucleotide in the cell; b) a step of expressing the exogenous polynucleotide in the cell; c) a step of analyzing the fatty acid composition in the cell; and d) a step of selecting cells in which Δ5 elongase produces DPA in cells selected at a rate of at least 60% and which is active with respect to EPA. SELECTED DRAWING : None COPYRIGHT : (C)2019, JPO&INPIT

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