FIELD : chemistry.SUBSTANCE : invention relates to the field of organic chemistry, namely to a method for producing 3-phenylamino-substituted furo[3, 4-c]pyridin-1(3H)-ones of the general formula (1), where X=C2H5, Y=para-CH3, X=CH3, Y=ortho-CH3; X=C2H5, Y=ortho-OH; X=CH3, Y=ortho-OCH3, comprising reacting 3-hydroxyfuro[3, 4-c]pyridin-1(3H)-one with an aromatic amine in a solvent at room temperature, characterized that as 3-hydroxyfuro[3, 4-c]pyridin-1(3H)-one is used 4-halogen-3-hydroxy-6-methyl-7-ethylfuro[3, 4-c]pyridin-1(3H)-one or 4-halogen-3-hydroxy-6, 7-dimethylfuro[3, 4-c]pyridin-1(3H)-one, and as aromatic amine use ortho- or para-toluidine, or 2-aminophenol, or ortho-anisidine, while the interaction is carried out in acetonitrile for 20–30 minutes, then evaporated 2/3 of the volume, the precipitated precipitate is filtered off, washed with propan-2-ol. .EFFECT : obtaining new derivatives furo [3, 4-c]pyridin-1(3H)-ones, which can be used in medicine, as substances with antitumor, antibacterial, including anti-tuberculosis and anti-malarial, activity.1 cl, 4 ex