专利名称 | 3 - Hydroxypyridine compound, its production and its use in medicine | ||
申请号 | JP2017551703 | 申请日 | |
公开(公告)号 | JP6473519B2 | 公开(公告)日 | 2015-12-14 |
申请(专利权)人 | 发明人 | 周雲隆; 蔡遂雄; 王光鳳; 焦玲玲; 閔平; 景羽; 郭明 | |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
The present invention relates to a compound of the following formula (I) or a pharmaceutically acceptable salt thereof, wherein R 1 and R 2 are independently H; R 3 is selected from H, a C 1 -C 7 straight-chain, and a branched or cyclic alkyl; and R 4 , R 5 , R 6 , R 7 , and R 8 are each independently selected from C 1 -C 7 alkyl, halo C 1 -C 7 alkyl and the like. The present invention also relates to a method for preparing the compound, pharmaceutical compositions comprising the compound or pharmaceutically acceptable salts thereof, and uses of the compound or pharmaceutically acceptable salt thereof in the preparation of a medicine for inhibiting HIF prolyl hydroxylase or a medicine for promoting the generation of endogenous EPO. |
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