| 专利名称 | ANTISENSE OLIGONUCLEOTIDES FOR MODULATING HTRA1 EXPRESSION | ||
| 申请号 | US15991326 | 申请日 | |
| 公开（公告）号 | US20190055564A1 | 公开（公告）日 | 2018-05-29 |
| 申请（专利权）人 | 发明人 | Rub閚 Alvarez S醤chez; Roberto Iacone; Peter Hagedorn; Susanne Kammler; S鴕en Ottosen; Sindri Traustason; Heidi Rye Hudlebusch; Lykke Pedersen; Marco Berrera; Andreas Dieckmann | |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
The present invention relates to antisense oligonucleotides (oligomers) that are complementary to HTRA1, leading to modulation of the expression of HTRA1. Modulation of HTRA1 expression is beneficial for a range of medical disorders, such as macular degeneration, e.g. age-related macular degeneration. |
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