| 专利名称 | ISOINDOLINONE INHIBITORS OF THE MDM2-P53 INTERACTION HAVING ANTICANCER ACTIVITY | ||
| 申请号 | US15763724 | 申请日 | |
| 公开(公告)号 | US20190055215A1 | 公开(公告)日 | 2016-09-29 |
| 申请(专利权)人 | 发明人 | Gianni CHESSARI; Steven HOWARD; Ildiko Maria BUCK; Benjamin David CONS; Christopher Norbert JOHNSON; Rhian Sara HOLVEY; David Charles REES; Jeffrey David ST DENIS; Emiliano TAMANINI; Bernard Thomas GOLDING; Ian Robert HARDCASTLE; Celine Florence CANO; Duncan Charles MILLER; Martin Edward M鋘tyl?NOBLE; Roger John GRIFFIN; James Daniel OSBORNE; Joanne PEACH; Arwel LEWIS; Kim Louise HIRST; Benjamin Paul WHITTAKER; David Wyn WATSON; Dale Robert MITCHELL | |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
The invention provides a compound of formula (I) : or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds. |
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