A controlled release pharmaceutical formulation is provided, comprising cyclosporine-loaded microparticles of a bioresorbable polymer comprising poly(D, L-lactide), wherein the mean diameter of the microparticles is in the range 20 μm to 40 μm. Also provided are medical uses of the pharmaceutical formulation, in particular in the treatment of uveitis, a process for production of the pharmaceutical formulation and injectable dosage forms, including those formulated for intravitreal injection.