The invention relates to medicine, in particular to devices for sighting finely needle puncture biopsy of prostate under ultrasonic control. The invention is simplification of design and was to increase the operation and reliability of adapter. Invention as follows. A guide adapter ultrasonic sensor, containing device for fastening to sensor, consisting of two hinge of a clamps, in one of which is made chute, and guide, on bracket, in which is made inclined chute, is fixed axis, of locking screw, on which it is installed g - shaped lever, and axis of rotation of lever is installed at an angle, equal to angle of inclination axis of groove in clamp, the working part of the tip lever, made in form of a wedge, at turn of is pressed to spring to the guide, and a guide is fixed between chute and working part nose, the pivotally connected clamp at installation on sensor are closed rotary retainer, which consists of screw, the proximal part of which is mounted in clamp on elastic axis between two bushings, and on distal part of screw is installed threaded head with stopping screw.