| 专利名称 | APPLICATION OF PEPTIDE Thr-Lys-Pro-Arg-Pro-Gly-Pro (SELANG) FOR DYSBIOSIS CORRECTION UNDER CHRONIC IMMOBILIZATION STRESS | ||
| 申请号 | RU2018134991 | 申请日 | |
| 公开（公告）号 | RU2681217C1 | 公开（公告）日 | 2018-10-03 |
| 申请（专利权）人 | 发明人 | Mukhina Aleksandra Yurevna; Svishcheva Mariya Vladimirovna; Medvedeva Olga Anatolevna; Kalutskij Pavel Vyacheslavovich; Shevchenko Alina Vladimirovna; Bobyntsev Igor Ivanovich; Andreeva Lyudmila Aleksandrovna; Myasoedov Nikolaj Fedorovich | |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
FIELD : pharmaceuticals.SUBSTANCE : invention relates to the use of the Thr-Lys-Pro-Arg-Pro-Gly-Pro (Selang) peptide for the correction of dysbiosis under chronic immobilization stress. Thr-Lys-Pro-Arg-Pro-Gly-Pro (Selang) peptide was dissolved in physiological saline and administered to experimental animals (rats) parenterally (intraperitoneally) at a dose of 250 mcg/kg body weight 15 minutes before the onset of stress in the volume of calculating 1 ml per 1 kg of body weight.EFFECT : invention provides an increase in the efficiency of dysbiosis correction under chronic immobilization stress.1 cl, 1 tbl, 1 ex |
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