专利名称 | - Substituted pyrazolone azo derivative or its salt in a pharmaceutical composition containing bicyclo and manufacturing method thereof | ||
申请号 | JP2018532117 | 申请日 | |
公开(公告)号 | JP2019506371A | 公开(公告)日 | 2017-01-16 |
申请(专利权)人 | 发明人 | ルウ、ユン; ジャン、シンホア; ジャン、ダイメイ | |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
Disclosed is a pharmaceutical composition comprising a bicyclo-substituted pyrazolon azo derivative or a salt thereof and a preparation method thereof. In particular, the pharmaceutical composition disclosed in the present invention comprises (Z)-5-(2-hydroxyl-3-(2-(3-methyl-5-oxo-1-(5, 6, 7, 8-tetrahydronaphthalene-2-yl)-1H-pyr azol-4(5H)-ylidene)hydrazino)phenyl)furan-2-carboxylic acid or a pharmaceutically acceptable salt thereof, and at least one filler optionally selected from cellulose, microcrystalline cellulose, lactose and starch. The composition has a good stability, dissolution rate and bioavailability, and the preparation process is simple, economical and quick. |
主管部门:海南中小企业服务 | 建设单位:海南商业联合会
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