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专利概况
专利名称 - Substituted pyrazolone azo derivative or its salt in a pharmaceutical composition containing bicyclo and manufacturing method thereof
申请号 JP2018532117 申请日
公开(公告)号 JP2019506371A 公开(公告)日 2017-01-16
申请(专利权)人 发明人 ルウ、ユン; ジャン、シンホア; ジャン、ダイメイ
专利来源 国家知识产权局 转化方式
摘要

Disclosed is a pharmaceutical composition comprising a bicyclo-substituted pyrazolon azo derivative or a salt thereof and a preparation method thereof. In particular, the pharmaceutical composition disclosed in the present invention comprises (Z)-5-(2-hydroxyl-3-(2-(3-methyl-5-oxo-1-(5, 6, 7, 8-tetrahydronaphthalene-2-yl)-1H-pyr azol-4(5H)-ylidene)hydrazino)phenyl)furan-2-carboxylic acid or a pharmaceutically acceptable salt thereof, and at least one filler optionally selected from cellulose, microcrystalline cellulose, lactose and starch. The composition has a good stability, dissolution rate and bioavailability, and the preparation process is simple, economical and quick.

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