PROBLEM TO BE SOLVED : To provide a method of treating a cancer or an infectious disease. SOLUTION : The present disclosure relates to novel recombinant fusion proteins, such as human antibody-based molecules called Vaccibodies, which are able to trigger both a T cell- and B cell immune response. The present disclosure also relates to a method of treating a cancer or an infectious disease by means of these specific fusion proteins. SELECTED DRAWING : Figure 1 COPYRIGHT : (C)2019, JPO&INPIT