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专利概况
专利名称 Bio-medical application for hydrogel polymers - flavonoid assembly and
申请号 JP2016540854 申请日
公开(公告)号 JP6484633B2 公开(公告)日 2014-09-01
申请(专利权)人 发明人 クリサワ、モトイチ; ぺ、キー・ヒュン
专利来源 国家知识产权局 转化方式
摘要

There is provided polymer-flavonoid conjugates. Flavonoid-grafted and flavonoid-terminated polymer conjugates are disclosed according to the invention. The linkage of flavonoids to the polymers has been achieved via thiol linkages. The inventive processes allow for making of the conjugates in high yield avoiding complex purification steps. The conjugates can be easily autoxidized to hydrogels with uses in many biomedical applications where a higher stability of the flavonoid is necessary. The hydrogels can be potentially used as viscosupplement, anti-adhesion film or dermal filler.

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