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专利概况
专利名称 Bicyclic heterocyclic derivative as inhibitor of the bromodomain
申请号 JP2016545312 申请日
公开(公告)号 JP6480944B2 公开(公告)日 2015-01-06
申请(专利权)人 发明人 サマジャダール、スサンタ; アビネニ、チャンドラセカール; サスマル、サンジタ; ホサハリ、サブラマンヤ
专利来源 国家知识产权局 转化方式
摘要

The present invention provides bicyclic heterocyclic derivatives of formula (I), which may be therapeutically useful, more particularly as bromodomain inhibitors; (I), in which R1, R2, R3, R4, L1, L2, Cy1, Cy2, X, n and dotted line are have the same meaning given in the specification, and pharmaceutically acceptable salts or pharmaceutically acceptable stereoisomers thereof that are useful in the treatment and prevention of diseases or disorder, in particular their use in diseases or disorder associated as bromodomain inhibitors. The present invention also provides preparation of the compounds and pharmaceutical formulations comprising at least one of bicyclic heterocyclic derivatives of formula (I), together with a pharmaceutically acceptable carrier, diluent or excipient therefor.

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