| 专利名称 | Brain-Targeting Prodrug for AMPA Receptor Synergist, and Pharmaceutical Applications Thereof | ||
| 申请号 | US16093754 | 申请日 | |
| 公开(公告)号 | US20190077821A1 | 公开(公告)日 | 2017-04-11 |
| 申请(专利权)人 | 发明人 | Song LI; Xinbo ZHOU; Dian XIAO; Wu ZHONG; Junhai XIAO; Zhibing ZHENG; Xingzhou LI; Yunde XIE; Xiaokui WANG | |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
Disclosed in the present invention is a compound of Formula (I), a geometric or optical isomer, a pharmaceutically acceptable salt, a solvate or a polymorph thereof. Also disclosed in the present invention is a composition comprising the compound of Formula (I), the geometric or optical isomer, the pharmaceutically acceptable salt, the solvate or the polymorph thereof. Also disclosed in the present invention is a use of the compound of Formula (I), the geometric or optical isomer, the pharmaceutically acceptable salt, the solvate or the polymorph thereof in the treatment of a disease or disorder such as a hypoglutamatergic condition, a neurodegenerative disease or respiratory depression, particularly in the treatment of a disease or disorder associated with AMPA receptor. |
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