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专利概况
专利名称 Brain-Targeting Prodrug for AMPA Receptor Synergist, and Pharmaceutical Applications Thereof
申请号 US16093754 申请日
公开(公告)号 US20190077821A1 公开(公告)日 2017-04-11
申请(专利权)人 发明人 Song LI; Xinbo ZHOU; Dian XIAO; Wu ZHONG; Junhai XIAO; Zhibing ZHENG; Xingzhou LI; Yunde XIE; Xiaokui WANG
专利来源 国家知识产权局 转化方式
摘要

Disclosed in the present invention is a compound of Formula (I), a geometric or optical isomer, a pharmaceutically acceptable salt, a solvate or a polymorph thereof. Also disclosed in the present invention is a composition comprising the compound of Formula (I), the geometric or optical isomer, the pharmaceutically acceptable salt, the solvate or the polymorph thereof. Also disclosed in the present invention is a use of the compound of Formula (I), the geometric or optical isomer, the pharmaceutically acceptable salt, the solvate or the polymorph thereof in the treatment of a disease or disorder such as a hypoglutamatergic condition, a neurodegenerative disease or respiratory depression, particularly in the treatment of a disease or disorder associated with AMPA receptor.

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