专利名称 | Modulators of the Cystic Fibrosis Transmembrane Conductance Regulator Protein and Methods of Use | ||
申请号 | US16129458 | 申请日 | |
公开(公告)号 | US20190077784A1 | 公开(公告)日 | 2018-09-12 |
申请(专利权)人 | 发明人 | Robert J Altenbach; Andrew Bogdan; Sylvain Couty; Nicolas Desroy; Gregory A Gfesser; Christopher Ga雝an Housseman; Philip R Kym; Bo Liu; Thi Thu Trang Mai; Karine Fabienne Malagu; Nuria Merayo Merayo; Olivier Laurent Picolet; Mathieu Rafa雔 Pizzonero; Xenia B Searle; Steven Emiel Van der Plas; Xueqing Wang; Ming C Yeung | |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
The invention discloses compounds of Formula (I), wherein A1, R1, R2, R3, R4, and n are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention. |
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