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专利概况
专利名称 FORMULATION
申请号 JP2018155174 申请日
公开(公告)号 JP2019038799A 公开(公告)日 2018-08-22
申请(专利权)人 发明人 JAMES JOSEPH HUSSEY; ANDREW GILBERT BRIGHT
专利来源 国家知识产权局 转化方式
摘要

PROBLEM TO BE SOLVED : To provide a pharmaceutically acceptable aqueous formulation of 1 -(4-{[4-(dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4, 6-dimorpholin-4-yl-1, 3, 5-triazin-2-yl)phenyl]urea that is (a) chemically stable on storage (e.g., at 25癈 and 60%RH), (b) that facilitates effective intravenous (or parenteral) administration of a drug to a mammal, including a human being, and (c) achieves a solution concentration of at least 6 mg/ml. SOLUTION : The present invention relates to a pharmaceutical aqueous formulation that is transparent solution, comprising the formulation, or a pharmaceutically acceptable alkanesulphonate salt thereof. SELECTED DRAWING : Figure 1 COPYRIGHT : (C)2019, JPO&INPIT

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