| 专利名称 | FORMULATION | ||
| 申请号 | JP2018155174 | 申请日 | |
| 公开(公告)号 | JP2019038799A | 公开(公告)日 | 2018-08-22 |
| 申请(专利权)人 | 发明人 | JAMES JOSEPH HUSSEY; ANDREW GILBERT BRIGHT | |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
PROBLEM TO BE SOLVED : To provide a pharmaceutically acceptable aqueous formulation of 1 -(4-{[4-(dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4, 6-dimorpholin-4-yl-1, 3, 5-triazin-2-yl)phenyl]urea that is (a) chemically stable on storage (e.g., at 25癈 and 60%RH), (b) that facilitates effective intravenous (or parenteral) administration of a drug to a mammal, including a human being, and (c) achieves a solution concentration of at least 6 mg/ml. SOLUTION : The present invention relates to a pharmaceutical aqueous formulation that is transparent solution, comprising the formulation, or a pharmaceutically acceptable alkanesulphonate salt thereof. SELECTED DRAWING : Figure 1 COPYRIGHT : (C)2019, JPO&INPIT |
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