FIELD : medicine.SUBSTANCE : invention relates to the field of medicine. Method for the regeneration of nerve fibers of blood vessels by gene stimulation of angiogenesis is proposed. In the distal part of the rat gastrocnemius muscle, in the region of ischemia, Ad-VEGF+ANG+GDNF combination is injected into 60 mcl NaCl with a quantity of virus particles of 2?1010.EFFECT : invention provides effective treatment of chronic lower limb ischemia, diabetic angiopathy, polyneuropathy of various origins.1 cl