| 专利名称 | MODULATORS OF THE CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR PROTEIN AND METHODS OF USE | ||
| 申请号 | WOIB18057020 | 申请日 | |
| 公开（公告）号 | WO2019053634A1 | 公开（公告）日 | 2018-09-13 |
| 申请（专利权）人 | 发明人 | ALTENBACH Robert J; BOGDAN Andrew; COUTY Sylvain; DESROY Nicolas; GFESSER Gregory A; HOUSSEMAN Christopher Ga雝an; KYM Philip R; LIU Bo; MAI Thi Thu Trang; MALAGU Karine Fabienne; MERAYO MERAYO Nuria; PICOLET Olivier Laurent; PIZZONERO Mathieu Rafa雔; SEARLE Xenia B; VAN DER PLAS Steven Emiel; WANG Xueqing; YEUNG Ming C | |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
The invention discloses compounds of Formula (I), wherein A1, R1, R2, R3, R4, and n are as defined herein. The present invention relates to compounds and their use in the treatment of cystic fibrosis, methods for their production, pharmaceutical compositions comprising the same, and methods of treating cystic fibrosis by administering a compound of the invention. |
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