Disclosed are an aqueous solution containing fullerene and 15-hydroxylpolyethylene glycol stearate, and a preparation method and the use thereof; a composition for external use containing fullerene and a water-soluble assistant, and a preparation method and the use thereof; an oral emulsion containing 10%-50% of a fullerene oil, 8%-20% of an emulsifier, 0.1%-0.2% of a co-emulsifier and the balance of deionized water, and a preparation method and the use thereof; and an oil-in-water type emulsion containing 10%-50% of a fullerene oil, 4%-17% of an emulsifier, 0.3%-1% of a stabilizer, 2%-9% of an excipient and the balance of water for injection, wherein same contains neither a solvent nor a co-solvent, and is stable at pH 7.3-7.4, and a preparation method and the use thereof.