PROBLEM TO BE SOLVED : To provide methods, compositions and kits containing phentolamine for improving visual performance. SOLUTION : A solution for use in improving visual performance contains phentolamine mesylate. The use is characterized by administering the solution to an eye of a patient once per day at or near the bedtime of the patient, where the patient experiences an increase in eye redness of grade one or less measured using the CCLRU Redness Grading Scale during the patient' s waking hours compared to the patient' s level of eye redness without receiving the solution containing phentolamine mesylate. The solution containing phentolamine mesylate is administered to the eye of the patient in an amount sufficient to improve visual performance for at least 20 hours. The solution containing phentolamine mesylate is administered to the eye of the patient as an eye drop. SELECTED DRAWING : None COPYRIGHT : (C)2019, JPO&INPIT