| 专利名称 | As inhibitor of spiro cycloheptane ROCK | ||
| 申请号 | JP2017502166 | 申请日 | |
| 公开(公告)号 | JP6499749B2 | 公开(公告)日 | |
| 申请(专利权)人 | BRISTOL MYERS SQUIBB COMPANY | 发明人 | ウラジミール・ラジアタ; ピーター・ダブリュー・グランツ; ジルン・フー; ワン・ユーフェン |
| 专利来源 | 国家知识产权局 | 转化方式 | |
| 摘要 |
The present invention provides compounds of Formula (I) : or stereoisomers, tautomers, or pharmaceutically-acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same. |
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