专利名称 | PALBOCICLIB SALTS | ||
申请号 | EP16859141 | 申请日 | |
公开(公告)号 | EP3368527A4 | 公开(公告)日 | |
申请(专利权)人 | Egis Gy骻yszergy醨 Zrt | 发明人 | LUK罜S Gyula; M罵V罭YOS Ede L醩zl? BERECZ G醔or; H蒁ER J醤os Levente; MILEN M醫y醩; PEREGI Bal醶s; GUDOR R骲ert; VOLK Bal醶s; T覶HN?LAURITZ M醨ia |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
The subject of the invention relates to various new salts of palbociclib, furthermore to their hydrate and solvate forms, such as the palbociclib hydrogen bromide (1 : 1) salt, the palbociclib hydrogen bromide (1 : 2) dihydrate salt, the palbociclib hydrogen chloride (1 : 1) salt Form E, the palbociclib sulphate (2 : 1) dihydrate salt, the palbociclib camsylate (1 : 1) salt, the palbociclib napsylate (1 : 1) salt, the palbociclib napsylate (1 : 2) dihydrate salt, the palbociclib tosylate (1 : 1) salt, the palbociclib citrate (1 : 1) monohydrate salt, the palbociclib maleate (1 : 1) salt Form I, the palbociclib maleate (1 : 1) salt Form II and the palbociclib oxalate (1 : 1) salt. The subject of the invention also relates to the production of the above palbociclib salts, medicinal preparations containing these and the medical use of the above forms. |
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