To provide agents for treating and/or preventing inflammatory disorders and/or autoimmune disorders.SOLUTION : The invention relates to a composition comprising : a polypeptide HP (hypothetical protein) comprising at least 20 amino acids in a specific sequence; a polynucleotide sequence encoding the polypeptide HP; and a host cell comprising the polynucleotide sequence or a host cell comprising an expression vector comprising the polynucleotide sequence. The composition may be capsulated, and usable as a pharmaceutical composition, a feedstuff, a food product, a dietary supplement or a food additive.SELECTED DRAWING : None